I have just been advised to change when I take Tamoxfin ie in  the evening. You also need to be aware that there are medications you cannot take with tamoxifen. Today is the first day in months that my head has been clear and hence googled side effects of Tamofin and found you. Dealing with menopausal symptoms related to hormone therapy can be hard. I'm determined to stay on Tamoxifen but I will and do ask for support around it if I find anything difficult. Here's some information that reassued me I wasn't going mad, hope they help you too. It's so great not to be the only one. "Low-dose tamoxifen is as effective as the standard dose," said study author Dr. … Tamoxifen is a hormonal therapy drug used: to reduce the risk of breast cancer coming back and to prevent a new cancer developing in the other breast – you take it for a number of years. The levels of estrogen will not necessarily decline if there is an issue with excessive aromatization. Tamoxifen for breast cancer treatment is prescribed for 5-10 years. Report It does have side effects—but they may be overestimated Despite its protective effects against cancer, some women stop taking tamoxifen because of side effects … Side effects of tamoxifen versus side effects of aromatase inhibitors. Is there anyone else on this fab chat forum that can advise us both. It is commonly used to treat breast cancer.It is also used to decrease the chance of breast cancer coming back in women who have received treatment for the disease. To any women due to start taking it I'd say take each day as it comes and don't worry about side effects that may never happen to you. Vaginal Dryness 7. If you and your doctor are considering tamoxifen as part of your treatment plan, tell your doctor if you smoke or have a history of blood clots or heart attack. Talk with your health care provider about ways to ease these and other side effects. Also I have the hot flushes night sweats, and my monthly visit has stopped, only been taking them since feb, hope the brain thing gets better as I'm sitting some exams soon and finding it hard to revise. Side effects, first year of treatment @ 20mg per day: Hot flashes, nausea, cramps, leg pain, loss of menstrual cyles. Gains… What gains? Chemo is a battle, but you will get through it if they offer FEC chemo, then ask them to give you your anti-sickness and steroids via IV rather than in tablet form. A woman who is choosing between Arimidex and tamoxifen should discuss the benefits and risks of each with her physician, including a review of her bone density history. What has knocked me for six is not the usual side effects that I'm having quite badly but that I'm also having problems thinking and working things out and speaking and remembering things. I hope this may help you, I know it is a worrying time I have asked to see the clinical psychologist because after treatment I too thought I would be feeling a lot more positive than I actually am. As an alternative to Clomid, which has been reported to have led to unwanted side effects such as visual disturbances in some users, Nolvadex can be employed. Thank you so much for your words. Dear ning, Hair thinning,rash and itching are listed as possible side effects of Tamoxifen. Drug-Induced Hot Flash 4. This medicine may increase your risk of developing blood clots. Angela, a Pink Hope Community Member who was diagnosed with breast cancer at 22, provides an overview of the drug Tamoxifen and shares her struggle with managing the side effects of taking this drug.. Tamoxifen tamoxifen… What can I write about this drug that has caused me personally so much anguish and turned my hormones upside down – five years is a long time to be taking this medication. I took the Tamoxifen for three weeks and all the side effects of constipation, mild vaginal itch, tired, nausea and weight gain immediately..uuuhg! I have been taking tamoxifen for a month now and have noticed that my fingers and toes have swollen alot, has anyone had experience of this? ), i had very bad hot flushes mainly at night , i started taking my tablets at night instead of during the day as i found hot flushes were easier to cope with during the day than at night ( i can be very grumpy if i don't get my sleep..ha ha ha )  i also put on about 1 1/2 stone in weight !!!! I've been on tamoxifen for about 4 month now and have a number of side effects. Common side effects include depression, nausea, vomiting, and headache. Having spoken to the oncologist though he advised that even if they did a scan if there was anything minute in another area there would be no benefit to start treatment early. bloating or swelling of the face, arms, hands, lower legs, or feet STAY in PAIN! hi jo thank you for sharin your experience my main question is if they dont know if theres anythin there for definate how will they know if its gone after your treatment i feel like there going to wait to see if anything happens before they start treatment well to me isnt that to late depending were the cancer emerges. 1. What has knocked me for six is not the usual side effects that I'm having quite badly but that I'm also having problems thinking and working things out and speaking and remembering things. Talk with your health care provider about ways to ease these and other side effects. Would be beneficial for my general hormones? Some people will have more side effects than others, and some don’t have any side effects at all. Thank you. Also, I am struggling to lose weight - any suggestions? Nolvadex (tamoxifen) PCT Proper Protocol. The length of treatment along with side effects can make it tough to complete treatment. Tamoxifen - managing adverse effects: Summary Tamoxifen is a selective oestrogen receptor modulator (SERM). Thanks. Thanks a lot. Will it get better? Tamoxifen's selective estrogen activation effects can cause some serious side effects, including blood clots, stroke, and endometrial cancer. hope all continues in the right direction for you . Feeling Weak If experienced, these tend to have a Less Severe expression 1. Check with your doctor right away if you have swelling and pain in your arms, legs, or stomach, chest pain, shortness of breath, loss of sensation, confusion, or problems with muscle control or speech. If you and your doctor are considering tamoxifen as part of your treatment plan, tell your doctor if you smoke … Leg swelling. The weight thing is awful too and so is the hair thinning. Tamoxifen oral tablet is used to treat and help prevent breast cancer. also by trying to help someone ( even if by only listening ! ) Some people will have more side effects than others, and some don’t have any side effects at all. i was put on tamoxifen back in june last year when i was diagnosed with stage 2 breast cancer . It seems to me that the older you are the worse the side effects. Common side effects include depression, nausea, vomiting, and headache. I would be happy to receive news and updates from Cancer Chat, Here's some information that reassued me I wasn't going mad, hope they help you too. It's really reassuring to hear it. I too wondered about the impact of tamoxifen on fibroids given its partial estrogen-like effects on some body tissues. Side effects from tamoxifen are not usually severe. The list goes on and on, but to compound it, when I told my doctors, they said, "oh, tamoxifen doesn't cause that. Skin rash. Possible Side Effects of Nolvadex: There are five possible side effects of Nolvadex that while possible are … We’re here to provide physical, financial and emotional support. Hi Sara,  have not had any of the side effects you have had so far. Bleeding Not Related To Menstrual Period 2. Coronavirus is having a huge impact on people living with cancer. However I was treated at Northampton General and their advise is not to go ahead with reconstruction until they know the outcome of the operation. Find out how likely side effects of tamoxifen are and side effects to report to your doctor, including common tamoxifen side effects, advice on tamoxifen and weight gain and blood clots symptoms The most common side effects associated with tamoxifen treatment are menopausal type symptoms, such as hot flushes and sweats, and vaginal itching, dryness or discharge. What has knocked me for six is not the usual side effects that I'm having quite badly but that I'm also having problems thinking and working things out and speaking and remembering things. My suggestion is to hang in there if you can, and see if the side effects go away. It's a safe forum where you can create or participate in support groups and discussions about health topics that interest you. it takes your mind off your own problems ......as mad as that seems....ha ha ha . I had radio and no chemo but I've been on Tamoxifen for a few months. Everyone reacts differently to drugs. Don't give it up it is one of the most effective treatments for breast cancer patients. The length of treatment along with side effects can make it tough to complete treatment. In some cases, tamoxifen may cause serious side effects, such as blood clots. I do  know how you are feeling following my operation I had to have 6 months chemo followed by 15 sessions of radiotherapy. © Macmillan Cancer Support, registered charity in England and Wales (261017), Scotland (SC039907) and the Isle of Man (604). I'm so sorry to hear about everything you have been going through as well as the cancer. Other side effects include: infection, sepsis, alopecia, constipation, cough, diarrhea, edema, increased serum aspartate aminotransferase, infrequent uterine bleeding, menstrual disease, ostealgia, vomiting, and weight gain. I don't get swollen fingers and toes but my feet suddenly feel very hot and painful as if I'm standing on burning coals so that it hurts to stand. I usually weight 128 and I'm 40, any pound feels like a ton. ; to treat [secondary breast cancer] to reduce risk of breast cancer developing in women at high risk because of their family history. Arimidex offers a small but real improvement over tamoxifen, and in general, side effects are minimal. On top of that, the lower dose -- just 5 milligrams daily -- came with fewer troubling side effects. Sure, it’s a popular PCT and users claim it’s a necessity after a steroid cycle, but what you may not realize is Nolvadex can cause a whole host of other issues, making it just as problematic as the steroid cycle itself. I hope I'm in the right place on the web site and that someone can help. A friend of mine who was diagnosed with breast cancer a year ago, and then had chemotherapy for nearly a year before having surgery to have the tumor removed is… I've lost weight rather than putting it on because I feel nauseous quite a lot of the time. hi ive had masc and recon 3wks ago and now been told ive got to av tamoxifen and make a choice of either having chemo or a injection for 2yrs called zoladex. I have seen my surgeon today and she confirmed that the swelling and weight issues are due to the tamoxifen. Tamoxifen CITRATE Side Effects by Likelihood and Severity COMMON side effects. Not even side effects of tamoxifen for gynecomastia can get away from this saying. I've only been on the Tamoxifen for a short while but I've noticed changes and it's slowly and steadily getting worse. Tamoxifen is a hormonal therapy drug used: to reduce the risk of breast cancer coming back and to prevent a new cancer developing in the other breast – you take it for a number of years. Irregular or loss of menstrual periods. Nolvadex (tamoxifen) PCT Proper Protocol. Over time symptoms seem to be getting better. Evista (raloxifene) a drug prescribed for the prevention and treatment of osteoporosis. My treatment finised in the middle of september. I don't get swollen fingers and toes but my feet suddenly feel very hot and painful as if I'm standing on burning coals so that it hurts to stand. 1 1/2 yrs ago. A company limited by guarantee, registered in England and Wales company number 2400969. Side effects of tamoxifen Tamoxifen's selective estrogen activation effects can cause some serious side effects, including blood clots, stroke, and endometrial cancer. WARNING: Uterine cancer, stroke, and blood clots in the lung have been reported when using tamoxifen for risk-reduction of breast cancer. Find everything you need to know about Tamoxifen (Nolvadex), including what it is used for, warnings, reviews, side effects, and interactions. The most significant is the hot flashes or "night sweats" she experiences, which cause her to have only 2-3 hours of sleep each night. It took me a long while to get used to the side effects (much more than one month). ; to treat [secondary breast cancer] to reduce risk of breast cancer developing in women at high risk because of their family history. I've been reading about how Tamoxifen can cause chemo brain on this web site and have found some research sites that talk about this. De Censi said the rate of side effects -- such as hot flashes, vaginal dryness, pain during intercourse and muscle pain -- was similar to the rate that occurred with a placebo pill. I will start a treatment with 20mg/day tamoxifen (Nolvadex) (10morning and 10 night) to treat gynecomastia. I have found mine to be very helpful. Like any drug, tamoxifen can cause side effects. driving me nuts. My oncologist is recommending tamoxifen but I've been reading about the side effects, the depression, ect, and I am really wondering if it is worth it. Weight gain (more common) or fluid retention . Having few or no side effects doesn't mean the drug is not effective. If this does not work surgery would be the only option. For many people, side effects improve within the first few months of starting the treatment. In men, possible side effects of tamoxifen include [ 87-89 ]: Blood clots in the large veins (deep vein thrombosis) Blood clots in the lungs (pulmonary emboli) one less thing to bother about ). Talk to your doctor about this risk. Thanks so much for this. Just about to take my supply but hopefully will have its full effect when I am asleep or having my nightly leg cramps! Tamoxifen may cause other side effects. Isle of Man company number 4694F. i don't always post but sometimes just reading peoples experiences helps . During the time I was taking it I had fatigue, hair thinning, a slower metabolism and thickened endometrium (known as tamoxifen uterus). I reckon the zapped my brain cells, lol. the only side effect I am having at present is vomitting at night. I have been taking tamoxifen since the beginning of January, no side effects for first 3 weeks, thought I’d got away with it, but sadly not. 5 Nolvadex side effects. Side effects of tamoxifen may include: Menopause-like symptoms, including hot flashes, night sweats and vaginal dryness. Talk to your doctor about this risk. Although both aromatase inhibitors and tamoxifen can cause menopausal symptoms such as hot flashes, many of their side effects differ. At long last I know that I am not alone and the Tamoxfin effects are real. Let’s review the 5 most troubling Nolvadex side effects. That I would be better off waiting to for any side effects before starting treatment. I'm really grateful to be on the Tamoxifen and doctors are going to try to slow down the effects so I'll post my progress on this chat page, but it's great that I'm not the only one! Think of the positive reason you take it if you can. Weight gain (more common) or fluid retention (edema). I found that this helped with any nausea feeling and managed to cope better with any side effects. I can't think things through properly, I can't make sentences make sense easily, I lose track of what I've been saying, I sometimes say the opposite of what I mean. there is always someone ready to talk or listen . I’m not sleeping very well due to hot flushes which triggers anxiety (all 3 have a knock on effect with each other....catch 22!!). Then the Tamoxifen. I am not taking any … See below for a comprehensive list of adverse effects. Like most breast cancer treatments, tamoxifen can cause side effects, including hot flashes and night sweats. I've lost weight rather than putting it on because I feel nauseous quite a lot of the time. After radiation her oncologist started her on tamoxifen. I am convinced the eczema is somewhat linked to hormone changes as the last time my skin was as bad was just after I had my daughter 16 years ago. I was on tamoxifen for 5 years after radiation and have been off of it for a year now. nicki t, I had a lumpectomy on 9th September my tumour had clear margins but there was a small amount of cancer in the one  lymph node taken.Because I am post menapausal I have been prescribed Femara rather than tamoxifen.If you have a breast care nurse why don't you ring her and tell her your confused and can she explain what your results mean? She has had severe side effects since taking the drug. i hope that this has helped , please ask if there are anyother side effects that i have forgotten about !!!!! I had 23 rad sessions, And now tamoxifen for 5 yrs. “In general, tamoxifen for five years reduces the probability of breast cancer recurrence by almost 50 percent, while risks of serious side effects are at around 1 percent or less,” he explained. [/color:r661bn6d] TAMOXIFEN blocks the effects of estrogen. Tamoxifen works by blocking estrogen receptors. How long have you been taking them? Like most breast cancer treatments, tamoxifen can cause side effects… The nurse said that this was normal! Registered office: 89 Albert Embankment, London SE1 7UQ. The ideal method to avoid making terrible choices is to collect information. What Is Side Effects of Tamoxifen for Gynecomastia. I was lucky enough to attend one of the meetings of patients and researchers. (Or at least not mess me up too much?). Generalized Weakness; Discharge From The Vagina 3. During the time I was taking it I had fatigue, hair thinning, a slower metabolism and thickened endometrium (known as tamoxifen uterus). They mean a lot. Learn about side effects, warnings, dosage, and more. I too feel like giving up but I'm too scared to. She said that in time it should settle. If you have any side effects, whether they’re listed here or not, talk to your GP or treatment team. I have just finished four rounds of chemo for ER+ Pr+ breast cancer. I'm on my own too and it's hard with children too. Commonly reported side effects of tamoxifen include: amenorrhea, fluid retention, hot flash, nausea, vaginal discharge, vaginal hemorrhage, weight loss, and skin changes. I've been reading about how Tamoxifen can cause chemo brain on this web site and have found some research sites that talk about this. Is Tamoxifen worth the side effects? Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Tamoxifen works by blocking the action of estrogen in breast tissue, which keeps estrogen-sensitive breast cancers from growing, according to the U.S. National Cancer Institute. Keep taking the tablets lol! I've been on tamoxifen for about 4 month now and have a number of side effects. Side effects from tamoxifen … Onward and upward!!!!!! As my cancer was very sensitive to hormones, it wasnt wise for me to stop taking the tablet until we can see if I can get over the side effects. ( but that was probably caused by siting around after my surgeries ! I take ages to think, remember and to write so it's great to hear that over time you find ways round it even though it obviously doesn't get better until you go off it. Tamoxifen (Nolvadex) prescribed for the prevention and treatment of breast cancer in men and women, and occasionally, to stimulate ovulation in women. my results from my masec were that the egdes of my breast tissue werent clear and now they dont no if i might have floating cells round my body is there anybody that understands my situation as im confussed and worried as i was prepared my results were going to be clear. I have been taking tamoxifen since the beginning of January, no side effects for first 3 weeks, thought I’d got away with it, but sadly not. The side effects are almost all gone now. Dealing with menopausal symptoms related to hormone therapy can be hard. ... Additionally, the WebMD Drugs & Medication Guide has product information and over 300 user reviews for tamoxifen that might discuss side effects and remedies. Also operating in Northern Ireland. Irregular or loss of menstrual periods. not complaining but hey I suppose we all different. but i found it very hard to concentrate on anything .thank god for spell check as i still can't focus when i type . Mood Changes 6. Side effects may include bronchitis, vomiting, insomnia, breast pain, and sore throat. Nolvadex is a trade name for the drug Tamoxifen. While the side effects of tamoxifen can be bothersome, they’re overshadowed by the reality that hormone-receptor-positive breast cancer can come back. Tamoxifen may increase the risk that you will develop cataracts (clouding of the lens in the eye) that may need to be treated with surgery. If experienced, these tend to have a Severe expression. Whatever cancer throws your way, we’re right there with you. The best advice I could give is take the tablet before bedtime that way some of the worst symptoms - I experienced dizziness at first, will be gone by the time you wake up. It is so brave of you to still think about other people. I must say my main symptoms/side effects have been some weight gain, typical menopausal symptoms. Talk to your doctor about this risk. Please support our emergency appeal. I gave them the list of side effects with the ones I had marked, and it was thrown in the waste basket in front of me. Now that I have quit taking it, the side effects come and go. My body has been through the mill this last year and I didn't know if it were a throw back to the chemo were chemo fog/brain was very real. I usually weight 128 and I'm 40, any pound feels like a ton. I now have to speak slowly so that my brain has time to work. Tamoxifen may increase the risk that you will develop other cancers, including liver cancer. I’m not sleeping very well due to hot flushes which triggers anxiety (all 3 have a knock on effect with each other....catch 22!!). These side effects may go away during treatment as your body adjusts to the medicine. There is a very useful thread on the subject of Tamoxifen on Breast Cancer Care site. I am haveing HORRIBLE side effects as in my legs, arms, back etc. Like any drug, tamoxifen can cause side effects. However, in some women who take it, tamoxifen causes problems with thinking. Been on Tamoxifen for 12 days now. He also said that dry skin - though not eczema - can be a TX side effect. If such side effects of Nolvadex occur, use will normally continue as treating breast cancer is without question the primary concern, and it is highly effective. WARNING: Uterine cancer, stroke, and blood clots in the lung have been reported when using tamoxifen for risk-reduction of breast cancer. Everyone reacts differently to drugs. When I saw my oncologist I too asked the question about floating cells as I was originally told they could not be sure. Having few or no side effects doesn't mean the drug is not effective. Yet there is a paucity of published data on tamoxifen and fibroids. ; Tamoxifen is also sometimes used to: SAN ANTONIO -- The antidepressant venlafaxine (Effexor), often given to breast cancer patients to treat the hot flashes associated with tamoxifen therapy, … I've been taking tamoxifen for 1 year and half now and these are the side effects that I have experienced so far! I gave them the list of side effects with the ones I had marked, and it was thrown in the waste basket in front of me. There is an increase in risk of developing blood clots or pulmonary embolism associated with Tamoxifen use particularly in women over age 50. Glad it has helped , think that when so many people are in the same situation it is nice just to be able to talk and some how that seems to make things a little better !!!! just gonna give it time to get used to it and take it as it comes and hope it settles. Duloxetinepka. I was on tamoxifen for 5 years after radiation and have been off of it for a year now. http://www.breastcancercare.org.uk/community/, Click here to find out more                  Download free Macmillan booklets. Hi Nicki, I had a masectomy December 2008, my cancer was also on the edges of the breast tissue. However, for some people they may cause distress and disrupt everyday life. I am being treated but if anyone else has any experience of this I'd love to know that I'm not the only one. These very positive results show that the benefits of tamoxifen are long-lasting. I've been reading about how Tamoxifen can cause chemo brain on this web site and have found some research sites that talk about this. Tamoxifen may cause other side effects. i should have had surgery 1st but as i was struggling to cope with a bitter divorce and sell my house the consultants thought it would be better to try and shrink the tumour with tamoxifen and zoladex injections . SERMs are nonsteroidal, triphenylethylene-based drugs that bind to oestrogen receptors, resulting in oestrogen agonist or oestrogen antagonist-like effects … Side effects of tamoxifen may include: Menopause-like symptoms, including hot flashes, night sweats and vaginal dryness. The severity some days feels like … Eventually my GP referred me to a dermatologist who diagnosed discoid eczema as a result of very dry skin. Breast cancer forum requires membership for participation - click to join. Talk to your doctor about this risk. i found that my brain just went to pieces......that might have been caused by trying to come to terms with having cancer and the fight that lay ahead !!!! Hi,  I have been on Tamoxifen for 41/2 years now and I will soon be coming to the end of my treatment. If anyone has been through this or currently going through this, I would love to know what treatment was used to help lessen the extreme pain. Tamoxifen may increase the risk that you will develop cataracts (clouding of the lens in the eye) that may need to be treated with surgery. I stopped taking the Tamoxifen because of the side effects and I was just honestlt MAD...madder than mad, don't know how to explain it. Now that I have quit taking it, the side effects come and go. There is a lot of research being done on the side effects of the aromatase inhibitors and tamoxifen at the University of Pittsburgh. I have the same problem, remembering etc. As an alternative to Clomid, which has been reported to have led to unwanted side effects such as visual disturbances in some users, Nolvadex can be employed. As for Tamoxifen, I took it from 2000-2005. Jo Jones. Please use one of the following formats to cite this article in your essay, paper or report: APA. “In general, tamoxifen for five years reduces the probability of breast cancer recurrence by almost 50 percent, while risks of serious side effects are at around 1 percent or less,” he explained. I was pretty lucky, besides weight gain, no other uncomfortable side effects. Folks often say that information is power, and though it's on the verge of turning into a cliché, it is still true. Wondered about the impact of tamoxifen are long-lasting levels of estrogen will not necessarily if... Health care provider about ways to ease these and other side effects along with side effects up too much )! Whether they ’ re right there with you Week http: //www.breastcancercare.org.uk/community/, Click here to find out more free! Reduce some of these side effects as in my Legs, Feet, Arms or 5... 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